Thermo LC Devices Thermo EASY-nLC Xcalibur VI
Developer: Thermo Fisher Scientific, Inc.
Description:
Thermo LC Devices Thermo EASY-nLC Xcalibur VI is a software component that integrates Thermo Fisher EASY-nLC nano-flow liquid chromatography systems with the Xcalibur data system. It enables direct control of the EASY-nLC from within Xcalibur for end-to-end LC–MS workflows, streamlining method setup, instrument control, and sequence execution for peptide- and protein-focused analyses.
Key capabilities:
- Seamless integration of EASY-nLC control within Xcalibur for coordinated LC–MS runs
- Method creation and editing, including gradient profiles, wash steps, and equilibration routines
- Real-time monitoring of system status (e.g., flow, pressure, valve states) and device diagnostics
- Sequence management for batch acquisition with consistent, reproducible LC settings
- Centralized logging and event reporting through the Xcalibur environment for traceability
- Designed for high-sensitivity nanoLC applications common in proteomics and complex peptide separations
Typical use:
- Setting up nano-flow gradients for peptide separations prior to MS detection
- Running unattended sample batches with synchronized LC–MS acquisition
- Monitoring EASY-nLC performance and resolving run-time alerts from the Xcalibur console
Compatibility and requirements:
- Requires a compatible Thermo Fisher EASY-nLC system and the Xcalibur data system
- Windows operating system (version support follows Xcalibur and device driver requirements)
- For specific model and version compatibility, refer to Thermo Fisher’s release notes
Note:
Functionality and supported features can vary by EASY-nLC model and Xcalibur version. For validated configurations and the latest updates, consult Thermo Fisher Scientific documentation or support.
Thermo LC Devices Thermo EASY-nLC Xcalibur VI is developed by Thermo Fisher Scientific, Inc.. The most popular version of this product among our users is 2.9.
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